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Products Piericidin A (Shaoguanmycin B, Antibiotic MT 1882-I, Antibiotic SN 198E, Antibiotic IT 143D, Piericidin A1)
| Catalogue number: | P4155 |
| Size: | 2mg |
| Form: | Supplied as a pale yellow oil. Soluble in ethanol, methanol, DMF or DMSO. |
| Purity: | ~95% by HPLC |
| Alternative names: | Shaoguanmycin B, Antibiotic MT 1882-I, Antibiotic SN 198E, Antibiotic IT 143D, Piericidin A1 |
| References: | 1. Evidence for a quinone binding site close to the interface between NUOD and NUOB subunits of Complex I. Prieur I. et al. Biochim. Biophys. Acta 2001, 1504, 173. 2. -->H+/2e- stoichiometry in NADH-quinone reductase reactions catalyzed by bovine heart submitochondrial particles. Galkin A.S. et al. FEBS Lett. 1999, 451, 157. 3. The 49-kDa subunit of NADH-ubiquinone oxidoreductase (Complex I) is involved in the binding of piericidin and rotenone, two quinone-related inhibitors. Darrouzet E. et al. FEBS Lett. 1998, 10, 34. 4. Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase. Friedrich T. et al. Eur J Biochem. 1994, 219, 691. |
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