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Plasmodium vivax, CSP, Recombinant (Malaria)

Cat no: P4256-79J

Plasmodium vivax, CSP, Recombinant (Malaria)

Outside sub-Saharan Africa, where P. falciparum infection is most common, P. vivax is the most common cause of malaria infection. While not as deadly as P. falciparum, it does negatively affect human health. Malaria infection is initiated when an infected Anophales mosquito injects sporozoites into a person's blood during a blood meal. The sporozoites migrate to and infect hepatocytes where they multiply asexually. The CSP is the major surface protein of sporozoites and form a dense coat on the parasite's surface. The CSP is involved in the motility of the sporozoite and the invasion of target cells. It is also required for sporozoite development in the mosquito. The protein has been extensively studied as a vaccine candidate. Vaccination with irradiated sporozoites has been shown to protect against malarial parasites with the sera of protected individuals recognizing CSP.\n\nSource: \nRecombinant corresponding to Plasmodium vivax CSP protein (malaria CSP pv) fusted to GST expressed in E. coli.\n\nApplications:\nSuitable for use in ELISA. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

P4256-79J

Size

1mg

Applications

ELISA

Form

Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.

Purity

~90% (SDS-PAGE)

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