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Podoplanin (Glycoprotein 36, GP36, PA2.26 Antigen, T1-alpha, T1A, Aggrus, PDPN, PSEC0003, PSEC0025)

Podoplanin (Glycoprotein 36, GP36, PA2.26 Antigen, T1-alpha, T1A, Aggrus, PDPN, PSEC0003, PSEC0025)

Cat no: P9104-91M

Supplier: United States Biological
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Expressed at the plasma membrane in epithelia involved in fluid transport, including type I alveolar epithelial cells, choroid plexus, and ciliary epithelium, the specific function of this protein has not been determined but it has been proposed as a marker of lung injury. T1A-2 has a broad tissue distribution with strong expression in lung, placenta and skeletal muscle. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P9104-91M
Reactivities: Human, Canine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Oakley GJ, Fuhrer K, Seethala RR, Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis. Modern pathology an official journal of the United States and Canadian Academy of Pathology, Inc 2008 Dec 21(12):1461-9.
Additional info: Recognizes human PDPN. Species sequence homology: Canine.

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