Quick Search
Products Prostaglandin D Synthase Inhibitor Screening Assay Kit
| Catalogue number: | 10006595 |
| Weight: | 0 |
| Form: | 96 Well |
| P type: | Assay Kits|Eicosanoids|Prostaglandins |
| Shipping temp: | -80 |
| Storage temp: | -80 |
| Additional info: | Prostaglandin D2 (PGD2) is synthesized by two distinct types of prostaglandin D synthase (PGDS), the lipocalin-type (L-PGDS) enzyme and the hematopoietic (H-PGDS) enzyme. PGD2 is produced by H-PGDS in large quantities by allergen-stimulated mast cells and acts as a pro-inflammatory mediator in allergic reactions. Selective inhibition of H-PGDS is therefore being pursued as a drug target for allergy treatment. The Cayman Chemical PGDS Inhibitor Screening Assay Kit is a complete package for the evaluation of PGDS isozyme-specific inhibitors. Each kit includes highly purified H-PGDS and L-PGDS, as well as PGH2 which serves as the enzyme substrate. A complete enzyme immunoassay (EIA) for the direct quantification of PGD2 quantification without prior methoximation is included in the kit. |
Get the Best Promotions
