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Products Prostaglandin E Synthase-1 (microsomal) Monoclonal Antibody (Clone 6C6)
| Catalogue number: | 10004350 |
| Hosts: | Mouse |
| Applications: | Immunocytochemistry, Immunohistochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | recombinant human mPGE synthase-1 |
| P type: | Antibodies|Eicosanoids |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Prostaglandin E synthase-1 (PGE synthase-1) catalyzes the isomerization of PGH2 to PGE2. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated PGs. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. PGE synthase-1 is a 16 kDa membrane associated protein with glutathione-dependent activity. The mRNA for PGE synthase-1 (PGES-1) is expressed in a variety of tissues including prostate, testes, and small intestine as well as in A549 and HeLa cells. PGES-1 protein expression is increased in A549 cells following treatment with IL-1(beta). Cayman Chemical's PGES-1 (microsomal) monoclonal antibody can be used for western blot, immunocytochemistry, and immunohistochemical (formalin-fixed paraffin-embedded tissue) analysis for mPGES-1 on samples of human origin. Other applications for use of this antibody have not yet been tested. |
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