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Products Prostaglandin E Synthase-1 (microsomal) Polyclonal Antibody
| Catalogue number: | 160140 |
| Hosts: | Rabbit |
| Applications: | Immunohistochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | human mPGE synthase amino acids 59-75 (CRSDPDVERSLRAHRND){7229} |
| P type: | Antibodies|Eicosanoids |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Prostaglandin E Synthase-1 (PGES-1) catalyzes the isomerization of PGH2 to PGE2. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. PGES-1 is a 16 kDa membrane-associated protein with glutathione-dependent activity. The mRNA is for PGES-1 is expressed in a variety of tissues including prostate, testes, and small intestine, as well as in A549 and HeLa cells. PGES-1 protein expression is increased in A549 cells following treatment with IL-1.beta. |
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