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Products Prostaglandin E Synthase-2 (microsomal) Polyclonal Antibody
| Catalogue number: | 160145 |
| Hosts: | Rabbit |
| Applications: | Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | synthetic peptide from the human mPGES-2 sequence conjugated to KLH (amino acids 221-235; VYGGKEARTEEMKWR) |
| P type: | Antibodies|Eicosanoids |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Prostaglandin E synthase-2 (microsomal) (mPGES-2) was recently identified as a second membrane-associated PGE2 producing enzyme. Unlike mPGES-1, mPGES-2 does not require glutathione for catalytic activity and is activated in the presence of a broad range of reducing agents. Northern blotting suggests this enzyme is found in high quantity in heart, brain, skeletal muscle, and kidney. Cayman Chemical's mPGES-2 polyclonal antibody can be used for Western blot analysis for mPGES-2 on samples from a variety of species including human, mouse, sheep, cow, and monkey. Use 1:1,000 dilution for formalin fixed paraffin embedded tissues. The antibody does not react with mPGES-1 or cytosolic PGES. Other applications for use of this antibody have not yet been tested. |
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