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Products Prostaglandin E Synthase (cytosolic, FL) Polyclonal Antibody
| Catalogue number: | 10209 |
| Hosts: | Rabbit |
| Applications: | Immunocytochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | full length, human recombinant cPGES |
| P type: | Antibodies|Eicosanoids |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Cytosolic PGE synthase (cPGES) is a glutathione-dependent enzyme with a predicted size of 18.6 kDa (23 kDa on SDS-PAGE). The enzyme is expressed in a wide variety of tissues and cells, the levels of which are unaffected by treatment with IL-1(beta) and TNF(alpha). However, enzyme expression increases approximately 3-fold in rat brain following LPS treatment. Microsomal PGE synthase (mPGES) is a 16 kDa protein expressed in a variety of tissues. In contrast to cPGES, mPGES protein expression is increases in A549 cells following treatment with IL-1(beta). The two enzymes show <10% homology at the amino acid level. |
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