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Prostaglandin I Synthase Monoclonal Antibody (Clone 3C8)

Cat no: 10247

Prostaglandin I Synthase Monoclonal Antibody (Clone 3C8)

Antigen: cell surface PGIS from follicular dendritic cell line HK . Host: mouse . Cross Reactivity: (+) human, mouse, and rat PGIS . Application(s): WB, FC, ICC, IHC, and IP

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SPECIFICATIONS

Catalog Number

10247

Applications

FC, ICC, IHC, IP, WB

Hosts

Mouse

Form

1 ea

P Type

Antibodies

Weight

0

Antigen

cell surface PGIS from follicular dendritic cell line HK

Storage Temp

-20

Shipping Temp

-20

Additional Info

Prostaglandin I synthase (PGIS) catalyzes the isomerization of PGH2 to PGI2. PGI2 (prostacyclin) is a potent vasodilator and inhibitor of platelet aggregation. PGIS is a membrane-bound hemoprotein localized primarily in endothelial cells. The cloned bovine and human enzymes contain 500 amino acids and a calculated molecular mass of 56,629 and 57,103, respectively. Northern blot analysis reveals that the mRNA for PGIS is expressed in a wide variety of human tissues and is particularly abundant in ovary, heart, skeletal muscle, lung, and prostate.

SUPPLIER INFO

Cayman Chemical Company

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