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Protein Tyrosine Phosphatase Type 4A, Member 3 (Protein Tyrosine Phosphatase 4A3, PTP4A3, Protein Tyrosine Phosphatase Type IVA Member 3, Protein Tyrosine Phosphatase Type IVA Protein 3, Potentially Prenylated Protein Tyrosine Phosphatase, Protein Tyrosin

Cat no: P9109-48D

Protein Tyrosine Phosphatase Type 4A, Member 3 (Protein Tyrosine Phosphatase 4A3, PTP4A3, Protein Tyrosine Phosphatase Type IVA Member 3, Protein Tyrosine Phosphatase Type IVA Protein 3, Potentially Prenylated Protein Tyrosine Phosphatase, Protein Tyrosin

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contain a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth. Two alternatively spliced variants exist.\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

P9109-48D

Size

100ug

Applications

WB

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in TBS, pH 7.2, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

References

Saha S et al. A phosphatase associated with metastasis of colorectal cancer. Science 294:1343-6 (2001). <PUBMED:11598267>

Additional Info

Species Crossreactivity: Human. Expected to crossreact with Mouse due to sequence homology.

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