PSTAIR (CDC2, CDC28A, CDKN1, P34CDC2, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase)

The cyclin-dependent protein kinases (CDKs) regulate major cell cycle transitions in eukaryotic cells. CDKs contain an evolutionary conserved 16 amino acid sequence called PSTAIR (EGVPSTAIREISLLKE) which distinguishes them from other protein kinases. The PSTAIRE motif found in prototypic CDC2 kinases. CDC2L1 is referred as PITSLRE B, based on the amino acid sequence of the region corresponding to the conserved CDC2 PSTAIRE box.\n\nUniProt Number:\nHuman(P06493), Mouse(P11440), Rat(P39951)\n\nGene ID:\nCDK1\n\nApplications:\nSuitable for use in Western Blot.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Handling:\nStore at -20?C for one year. After reconstitution, store at 4?C for one month. Can also be aliquoted and stored frozen at -20?C for long term.\nAvoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

145105

Size

100ug

Applications

WB

Hosts

Mouse

Reactivities

Hum, Mouse

Form

Ascites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.

P Type

Mab

Isotype

IgG1

References

1. Xiang, J.; Lahti, J. M.; Grenet, J.; Easton, J.; Kidd, V. J. : Molecular cloning and expression of alternatively spliced PITSLRE protein kinase isoforms. J. Biol. Chem. 269: 15786-15794, 1994.

Additional Info

Recognizes human and mouse PSTAIR. No crossreactivity with other proteins.