Home  >  Products  >  PTP4A1 (Protein Tyrosine Phosphatase Type IVA 1, PTP(CAAXI), Protein-tyrosine Phosphatase 4a1, Protein-tyrosine Phosphatase of Regenerating Liver 1, PRL-1, PRL1, PTPCAAX1)
PTP4A1 (Protein Tyrosine Phosphatase Type IVA 1, PTP(CAAXI), Protein-tyrosine Phosphatase 4a1, Protein-tyrosine Phosphatase of Regenerating Liver 1, PRL-1, PRL1, PTPCAAX1)

PTP4A1 (Protein Tyrosine Phosphatase Type IVA 1, PTP(CAAXI), Protein-tyrosine Phosphatase 4a1, Protein-tyrosine Phosphatase of Regenerating Liver 1, PRL-1, PRL1, PTPCAAX1)

Cat no: P9109-45X1

Supplier: United States Biological
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Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: P9109-45X1
Reactivities: Human, Mouse, Rat, Canine
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Min SH, Kim DM, Heo YS, Kim YI, Kim HM, Kim J, Han YM, Kim IC, Yoo OJ. New p53 target, phosphatase of regenerating liver 1 (PRL-1) downregulates p53. Oncogene. 2009 Jan 29;28(4):545-54. 2. Achiwa H, Lazo JS. PRL-1 tyrosine phosphatase regulates c-Src levels, adherence, and invasion in human lung cancer cells. Cancer Res. 2007 Jan 15;67(2):643-50.
Additional info: Recognizes human PTP4A1. Species sequence homology: Canine, mouse and rat.

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