Purified anti-HDAC1

Cat no: 607401

Supplier: BioLegend

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Description
Additional Information

HDAC1 (histone deacetylase 1) is a 65 kD member of the Class I histone deacetylase family, similar to the yeast RPD3 protein. This nuclear protein operates in concert with histone acetyltransferases to control core histone acetylation in highly conserved lysine residues. HDAC activity has been associated with transcriptional repression and nucleosomal condensation. HDAC1 can be modified by phosphorylation and sumoylation. HDAC1 has been shown to interact with protein phosphatase 1, Rb, MyoD (muscle cells), and the mSin3a co-repressor complex. The Poly6074 antibody has been shown to be useful for Western blotting of human and mouse HDAC1.

Catalogue number:	607401
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Immunofluorescence, Western Blot
Size:	50 microl
Clone:	Poly6074
Gene:	3065
Dilutions:	Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 10 microl per 5 ml antibody dilution buffer for each mini-gel. For immunofluorescence microscopy: Use a starting dilution of 1:100. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store frozen at -20 C.
Antigen:	Synthetic peptides, a.a. 1-5, 433-448, and 467-482
Isotype:	Rabbit Polyclonal
Clonality:	Polyclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	-20 C
Alternative names:	Histone deacetylase 1