Purified anti-TdT

Cat no: 649301

Supplier: BioLegend

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Description
Additional Information

Terminal deoxynucleotidyl transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. TdT is a specialized DNA polymerase expressed early in pre-B and pre-T lymphoid cell development, and in acute lymphoblastic leukemia/lymphoma cells. TdT contributes to the generation of junctional diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. The L10-2 clone has been shown to be useful for western blotting of human and mouse TdT.

Catalogue number:	649301
Reactivities:	Human, Mouse
Hosts:	Mouse
Applications:	Western Blot
Size:	25 microg
Clone:	L10-2
Gene:	1791
Dilutions:	Each lot of this antibody has been quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 1.0 microg per ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
Storage buffer:	Upon receipt, store undiluted at 4C.
Concentration:	0.5 mg/ml
Antigen:	TdT
Isotype:	Mouse IgG2b, kappa
Clonality:	Monoclonal
Regulatory status:	RUO
Shipping temp:	Ambient RT
Storage temp:	4 C
Alternative names:	DNTT; TDT; DNA nucleotidylexotransferase; Terminal addition enzyme; Terminal deoxynucleotidyltransferase