RAB2 (Ras-Related Protein Rab-2A, RAB2A)

Cat no: R0006-50C

Supplier: United States Biological

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Description
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Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rabs are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking. The mammalian RAB proteins show striking similarities to the S. cerevisiae YPT1 and SEC4 proteins, Ras-related GTP-binding proteins involved in the regulation of secretion. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml, HeLa cell lysates observed on ~23,18kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	R0006-50C
Reactivities:	Human, Mouse, Rat, Bovine, Porcine
Hosts:	Goat
Applications:	Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Tisdale EJ, Balch WE. Rab2 is essential for the maturation of pre-Golgi intermediates. J Biol Chem 1996 Nov 15;271(46):29372-9.
Additional info:	Recognizes human RAB2. Species sequence homology: Bovine, mouse, porcine and rat.

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RAB2 (Ras-Related Protein Rab-2A, RAB2A)

Cat no: R0006-50C

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