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Rabbit Anti-Human 5-Methylcytosine monoclonal antibody, clone SN342

Rabbit Anti-Human 5-Methylcytosine monoclonal antibody, clone SN342

Cat no: CABT-BL8512

Supplier: Creative Diagnostics
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Rabbit Anti-Human 5-Methylcytosine monoclonal antibody for ELISA, ICC, IP, IF. Methylation of DNA cytosine bases plays important roles in the regulation of gene transcription. It has been estimated that 60 to 90% of the cytosines in CpG dinucleotides are methylated. An increase in methyl-CpG correlates with transcriptional silencing for the whole chromosome especially in developmentally regulated genes. Methylation is believed to lead to transcriptional silencing by multiple mechanisms including alteration of transcription factor binding to promoters and alteration in chromatin structure.
Catalogue number: CABT-BL8512
Reactivities: Human
Hosts: Rabbit
Applications: ELISA
Conjugates: Unconjugated
Clone: SN342
Target: Cytosine
Isotype: IgG
Clonality: Monoclonal
Storage temp: -20°C, Avoid Freeze/Thaw Cycles

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