Rabbit Anti-Human CD7 monoclonal antibody, clone TQ05

Rabbit Anti-Human CD7 monoclonal antibody for IHC-P. CD7 (gp40, Leu9) is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

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SPECIFICATIONS

Catalog Number

CABT-L1724

Hosts

Rabbit

Reactivities

Hum

Conjugates

Unconj

Clone

TQ05

Target

CD7

Gene Id

55136

Isotype

IgG

Clonality

Monoclonal

Storage Temp

2-8В°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.