Rabbit Anti-Human ErbB3 monoclonal antibody for IHC-P. The gene for c-erbB-3/HER-3 is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6.2kb mRNA which is translated into a 160/180kDa glycoprotein. The c-erbB-3/HER-3 gene encodes secreted as well as transmembrane receptor tyrosine kinase due to alternative splicing. The c-erbB-3 is overexpressed in a variety of tumors including breast, stomach, pancreas, and colon.