Rabbit Anti-Human MALT1 polyclonal antibody for IHC-P, WB. MALT-1 was independently identified as a member of the human paracaspase family and an interacting partner of B cell lymphoma. Two alternatively spliced transcript variants encoding different isoforms (a and b) have been described for the MALT-1 gene. Human MALT isoform a is an amino acid protein of 824 amino acids, and human MALT-2 isoform b is an amino acid protein of 813 amino acids. MALT-1 is thought to play a role in NFkappaB signaling by enchancing NF kappaB activation through interaction with BCL-10. Interaction between MALT-1 and BCL-10 mediates IKK activation in vitro through facilitating the ubiquitination of NEMO by the ubiquitin conjugating enzyme UBC13.