Rabbit Anti-Human Mmp23 polyclonal antibody for IHC-P. MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region, and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs) . MMPs and TIMPs play a significant role in regulating angiogenesis. MMP-23 transcripts have been detected in reproductive organs like ovary, testis and prostate. MMP-23 is inhibited by TIMP-1.