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Rabbit Anti-Human PML polyclonal antibody

Rabbit Anti-Human PML polyclonal antibody

Cat no: DCABH-2098

Supplier: Creative Diagnostics
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Rabbit Anti-Human PML polyclonal antibody for IHC-P. The PML protein is a zinc finger transcription factor expressed as three major transcription products due to alternative splicing. The gene encoding human PML maps to chromosome 15q22. The t (15; 17) (q22; q11.2-q12) chromosomal trans-location of the retinoic acid receptor alpha (RARalpha) gene occurs in virtually all cases of acute promyelocytic leukemia and results in the expression of a PML/RARalpha chimeric protein of 106kDa. Myeloid precursor cells expression the PML/RARalpha chimera fail to differentiate and exhibit an increased growth rate consequent to diminished apoptosis.
Catalogue number: DCABH-2098
Reactivities: Human
Hosts: Rabbit
Conjugates: Unconjugated
Gene: 5371
Target: PML
Isotype: IgG
Clonality: Polyclonal
Storage temp: 2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

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