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Rad21 (Double Strand Break Repair Protein Rad21 Homolog, FLJ25655, FLJ40596, hHR21, HR21, HRAD21, KIAA0078, MCD1, Nuclear Matrix Protein 1, NXP-1, NXP1, RAD21 Homolog, SCC1, SCC1 Homolog) (Agarose)

Cat no: R0447-02A

Rad21 (Double Strand Break Repair Protein Rad21 Homolog, FLJ25655, FLJ40596, hHR21, HR21, HRAD21, KIAA0078, MCD1, Nuclear Matrix Protein 1, NXP-1, NXP1, RAD21 Homolog, SCC1, SCC1 Homolog) (Agarose)

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pmbe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chrom specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.\n\nApplications: \nSuitable for use in Immunoprecipitation. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degrees C. Aliquots are stable for at least 3 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

R0447-02A

Size

100ug

Applications

IP

Hosts

Rabbit

Reactivities

Hum

Conjugates

Agarose

Form

As reported

P Type

Pab

Purity

Serum

Additional Info

Reacts with human Rad21. Other species have not been tested. Mouse expected to react based upon sequence identity.

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