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RARRES1, Recombinant, Human, aa43-294, His-Tag (Retinoic Acid Receptor Responder Protein 1 Isoform 1, TIG1)

Cat no: 137177

RARRES1, Recombinant, Human, aa43-294, His-Tag (Retinoic Acid Receptor Responder Protein 1 Isoform 1, TIG1)

Retinoic acid receptor responder protein 1 isoform 1, also known as RARRES1, belongs to the TIGs (Tazarotene-induced gene) family. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. \n \nSource: \nRecombinant protein corresponding to human RARRES1, fused to His-tag at N-terminal expressed in E.coli.\n\nMolecular Weight: \n~31.3kD (275aa)\n\nAA Sequence:\nMGSSHHHHHH SSGLVPRGSH MGSPDDPGQP QDAGVPRRLL QQAARAALHF FNFRSGSPSA LRVLAEVQEG RAWINPKEGC KVHVVFSTER YNPESLLQEG EGRLGKCSAR VFFKNQKPRP TINVTCTRLI EKKKRQQEDY LLYKQMKQLK NPLEIVSIPD NHGHIDPSLR LIWDLAFLGS SYVMWEMTTQ VSHYYLAQLT SVRQWKTNDD TIDFDYTVLL HELSTQEIIP CRIHLVWYPG KPLKVKYHCQ ELQTPEEASG TEEGSAVVPT ELSNF\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

137177

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.4M Urea, 10% glycerol.

Purity

~90% (SDS-PAGE)

References

1. Kwong J., et al. (2005) J Cancer.113:386-392.

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