Recombinant Anti-ZIKA Envelope protein monoclonal antibody for ELISA, FC, Neut. Zika virus spreads to people primarily through the bite of an infected Aedes species mosquito, but it can also be sexually transmitted. Zika virus was first discovered in 1947 and is named after the Zika Forest in Uganda. In 1952, the first human cases of Zika were detected. Zika virus has become a highly researched disease due to increase in incidences from 2007 to 2016, when the virus spread eastward, across the Pacific Ocean to the Americas. In 2015–16 Zika virus epidemic reached pandemic levels. The Zika envelope (E) protein composes the majority of the virion surface and it is involved with replication, such as host cell binding and membrane fusion.