Catalogue number: | 10009411 |
Hosts: | Rabbit |
Applications: | Western Blot |
Weight: | 0 |
Form: | 1 ea |
Antigen: | peptide corresponding to amino acid residues from the C-terminal region of rat RSK2 |
P type: | Antibodies|Intracellular Signaling |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | The p90 ribosomal S6 kinases (RSK) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits. Recent work suggests that RSK2 exerts a tonic regulation on G protein-coupled signaling. |