S100 Protein, beta, beta

S100 belongs to the family of calcium binding proteins such as calmodulin and troponin C. S100A is composed of an alpha and beta chain whereas S100B is composed of two beta chains. Antibody to S100 stains Schwannomas, ependymomas, astrogliomas, almost all benign and malignant melanomas and their metastases. S100 protein is also expressed in the antigen presenting cells such as the Langerhans cells in skin and interdigitating reticulum cells in the paracortex of lymph nodes. S100 is a nervous tissue specific soluble protein made in glial cells. Present in sweat glands chongrocytes and myoepithelial cells. May be found as cytoplasmic, membranous or mixed throughout the areas of tumor. Usually cytoplasmic when present in normal tissues.\n\nApplications:\nSuitable for use in Western Blot, ELISA and Immunoaffinity Purification. Other applications not tested\n\nRecommended Dilutions:\nOptimal dilutions to be determined by researcher.\n\nMatched Pair:\nS0052-11 or S0052-15: Suitable for use as the capture antibody.\nS0052-14: Suitable for use as the detection antibody.\n\nHybridoma: \nSp2/0 myeloma cells with spleen cells from Balb/c mice.\n\nSource: Ascites\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) and aliquot. Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts