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S100Z, aa1-99, Recombinant, Human (S100 Calcium Binding Protein Z, Gm625, Protein S100-Z, S100 Calcium-binding Protein Z, S100-zeta)

Cat no: S0052-06Z1

S100Z, aa1-99, Recombinant, Human (S100 Calcium Binding Protein Z, Gm625, Protein S100-Z, S100 Calcium-binding Protein Z, S100-zeta)

S100 calcium binding protein Z, also known as S100Z, is member of the S100 protein family. S100 proteins are small dimeric members of the EF-hand superfamily of Ca(2+) binding proteins thought to participate in mediating intracellular Ca(2+) signals by binding to and thereby regulating target proteins in a Ca(2+)-dependent manner. There are differences in the expression level of S100Z mRNA in various tissues. The highest levels were found in spleen and leukocytes.S100Z gene expression appears to be deregulated in some tumor tissues, compared to expression in their normal counterparts.\n\nSource:\nRecombinant corresponding to aa1-99 of human S100Z 6x his tagged, expressed in E.coli. \n\nAA Sequences: \nMGSSHHHHHH SSGLVPRGSH MPTQLEMAMD TMIRIFHRYS GKERKRFKLS KGELKLLLQR ELTEFLSCQK ETQLVDKIVQ DLDANKDNEV DFNEFVVMVA ALTVACNDYF VEQLKKKGK\n\nMolecular Weight: 13.7kD (119aa), confirmed by MALDI-TOF\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20 degrees C. Aliquots are stable for at least 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S0052-06Z1

Size

100ug

Form

Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 20% glycerol, 1mM EDTA, 50mM sodium chloride.

Purity

~95% (SDS-PAGE).

References

1. Zhou Y., et al. (2006) Proteins. 65(3):643-55. 2. Hoque CW., et al. (1992) J Biol Chem. 267(19): 13340-7.

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