SDF-1 Antibody

Cat no: 251289

Supplier: ABBIOTEC

0 reviews | Write a Review Pencil

Description
Additional Information

Stromal-Derived Factor (SDF-1) is a chemoattractant active on T-lymphocytes and monocytes, but not neutrophils. This cytokine activates the C-, Xenopus/Amphibian,-C chemokine receptor C, Xenopus/Amphibian,CR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemota, Xenopus/Amphibian,is. SDF-1-alpha (3-67) and SDF-1-beta (3-72) show a reduced chemotactic activity. Binding to cell surface proteoglycans inhibits formation of SDF-1-alpha (3-67),Porcinereserving the activity of SDF-1 on local sites. SDF-1 acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the Lyn kinase. SDF-1 stimulates migration of monocytes through its receptor, C, Xenopus/Amphibian,CR4, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins.

Catalogue number:	251289
Reactivities:	Human, Mouse, Chicken/Bird, Porcine, Rabbit
Applications:	Immunohistochemistry
Size:	0.1 mg
Accession:	P48061
Antigen:	KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human SDF-1.
Format:	Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type:	Rabbit Polyclonal Antibody
Isotype:	Rabbit Ig
Additional info:	SDF-1; C, Xenopus/Amphibian,CL12; Stromal cell-derived factor 1; hSDF-1; C-, Xenopus/Amphibian,-C motif chemokine 12; Pre-B cell growth-stimulating factor; Intercrine reduced in hepatomas; IRH; PBSF; hIRH; SDF1; SDF1A; SDF1B