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SFRP2, CT (Secreted Frizzled-related Protein 2, FRP-2, SARP1, SDF-5, Secreted Apoptosis Related Protein 1)

Cat no: S1012-87T

SFRP2, CT (Secreted Frizzled-related Protein 2, FRP-2, SARP1, SDF-5, Secreted Apoptosis Related Protein 1)

sFRP2, otherwise known as SARP-1 (secreted apoptosis-related protein 1), is a member of the secreted frizzled-related protein family which interact directly with Wnt, to act as soluble modulators of Wnt signalling. Several studies have linked the epigenetic silencing of the sFRP2 gene with cancer, including breast cancer, colorectal cancer, gastric cancer, renal cell carcinoma and acute myeloid leukemia.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:32,000\nWestern Blot: 1-3ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S1012-87T

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum

Form

Supplied as a liquid in Tris-saline, pH 7.3, 0.02% sodium azide, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG

Additional Info

Recognizes an epitope within the C-terminal (CT) region of human sFRP2 at ~38kD in duodenum cell lysates. Species sequence homology: mouse, rat, canine.

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