SLC7A11 (Cystine/Glutamate Transporter, Amino Acid Transport System xc-, Calcium Channel Blocker Resistance Protein CCBR1, Solute Carrier Family 7 Member 11, xCT)

Sodium-independent, high-affinity exchange of anionic aa with high specificity for anionic form of cystine and glutamate.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:128,000\nWestern Blot: 0.02-0.06ug/ml, observed in human spleen and thymus lysates on ~50kD bands\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

S5329-08L

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum, Can

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

References

1. Kaleeba JA, Berger EA. Kaposi's sarcoma-associated herpesvirus fusion-entry receptor: cystine transporter xCT. Science. 2006 Mar 31;311(5769):1921-4.

Additional Info

Recognizes human SLC7A11. Species sequence homology: Canine.