SMAD1/5/8/9 Polyclonal Antibody

Antigen: two synthetic peptides corresponding to amino acids 18-33 and amino acids 315-330 of human SMAD1 . Host: rabbit . Cross Reactivity: (+) Human, mouse, and rat SMAD1/5/8/9; predicted to react with with chicken, chimpanzee, invertebrates, mammals, porcine, Xenopus, and zebrafish . Application(s): WB . SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD5, SMAD8, and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8, and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them

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SPECIFICATIONS

Catalog Number

10822

Applications

WB

Hosts

Rabbit

Form

1 ea

P Type

Antibodies|Intracellular Signaling

Weight

0

Antigen

two synthetic peptides corresponding to amino acids 18-32 and amino acids 315-330 of human SMAD1

Storage Temp

-20

Shipping Temp

-20

Additional Info

SMADs are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs:SMAD1, SMAD2, SMAD3, SMAD5, SMAD8, and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8, and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature. This antibody is expected to detect SMAD 1, 5, 8, and 9.