Antigen: two synthetic peptides corresponding to amino acids 18-33 and amino acids 315-330 of human SMAD1 . Host: rabbit . Cross Reactivity: (+) Human, mouse, and rat SMAD1/5/8/9; predicted to react with with chicken, chimpanzee, invertebrates, mammals, porcine, Xenopus, and zebrafish . Application(s): WB . SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD5, SMAD8, and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8, and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them