Antigen: synthetic peptides corresponding to amino acids 186-199 and 509-523 of human SMAD4 . Host: rabbit . Cross Reactivity: (+) Human, new world monkey, mouse, and rat SMAD4; predicted to react with chicken, bovine, Drosophila, porcine, pufferfish, ovine, Xenopus SMAD4 . Application(s): WB . SMAD4 is a common-mediator SMAD (co-SMAD) that is part of a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor (beta) superfamily.
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