SNAI1 (Zinc Finger Protein SNAI1, Protein Snail Homolog 1, Protein Sna, SNAH)

Cat no: S1014-67L3

Supplier: United States Biological

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Involved in the epithelial to mesenchymal transition (EMT) and formation and maintenance of embryonic mesoderm By similarity. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 0.1-0.3ug/ml, observed in lysates of cell line A431 and human kidney lysate on ~28kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	S1014-67L3
Reactivities:	Human, Mouse, Rat
Hosts:	Goat
Applications:	ELISA, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Vega S, Morales AV, Ocana OH, Valdes F, Fabregat I, Nieto MA. Snail blocks the cell cycle and confers resistance to cell death. Genes Dev. 2004 May 15;18(10):1131-43.
Additional info:	Recognizes human SNAI1. Species Crossreactivity: Mouse. Species sequence homology: Rat.

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SNAI1 (Zinc Finger Protein SNAI1, Protein Snail Homolog 1, Protein Sna, SNAH)

Cat no: S1014-67L3

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