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Sox 1 (High Mobility Group (HMG) Transcription Factor)

Cat no: S5364-01A

Sox 1 (High Mobility Group (HMG) Transcription Factor)

SOX1 (SRY-related HMG box 1) is a 39 kD transcription factor that belongs to the SRY family of HMG box proteins of which there are 30 members in vertebrates. Group B contains SOX1 along with SOX2, SOX3, SOX14 and SOX21; each of these factors share greater than 90% homology in their respective HMG box region. SOX1 maintains neural cells in an undifferentiated state and has been used as a marker for neural stem cells. Human and mouse SOX1 share 97% amino acid sequence identity.\n\nApplications: \nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.1ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nLyophilized powder may be stored at 4 degrees C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S5364-01A

Size

100ug

Applications

WB

Hosts

Mouse

Reactivities

Hum, Mouse

Form

Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol, 0.02% SODIUM AZIDE.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

Additional Info

Recognizes endogenous, human/mouse SOX1. \nShows 10% crossreactivity wth rhSOX-2, and no crossreactivity with rhSOX-3, -5, -6, -7, -9, -10, -11, -15, -17, or rmSOX-21.

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