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sPLA2 (human Type IIA) EIA Kit

Cat no: 585000

sPLA2 (human Type IIA) EIA Kit

Cayman's sPLA2 EIA Kit is an immunometric (i.e. "sandwich") assay that can be used for the quantification of sPLA2 in plasma, synovial fluid, and other sample matrices. Each kit contains AChE:sPLA2 antibody conjugate, antiserum, human recombinant sPLA2 standard, Ellman's reagent, EIA buffer, wash buffer, Polysorbate 20, plates pre-coated with sPLA2 capture antibody, and complete instructions.

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SPECIFICATIONS

Catalog Number

585000

Form

96 Well

P Type

Assay Kits|Phospholipids|Eicosanoids

Weight

0

Storage Temp

-20

Shipping Temp

-20

Additional Info

sPLA2 are found in the venom of certain snakes (Types IA, IIA, and IIB from vipers, cobras, rattlesnakes, and kraits), in pancreatic juices (Type IB), in rat and murine testes (Type IIC), in placenta, synovial fluids and platelets (Type IIA), and in heart, placenta, lung, mast cells and P388D1 macrophages (Type V). Until 1994 the sPLA2 responsible for the release of arachidonic acid in inflammation was believed to be Type IIA. Although recently discovered isoforms of PLA2 clearly contribute to the release of arachidonic acid, sPLA2 (Type IIA) continues to be a protein of interest in the field of inflammation. This EIA is specific for Type IIA sPLA2, and does not crossreact with Type I, Type IV or Type V PLA2, or inflammatory mediators such as tumor necrosis factor, interleukin-1, or platelet activating factor. Cayman

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