Catalogue number: | 160500 |
Hosts: | Mouse |
Applications: | Immunohistochemistry, Immunoprecipitation, Western Blot |
Weight: | 0 |
Form: | 1 ea |
Antigen: | human recombinant sPLA2 Type IIA |
P type: | Antibodies|Enzymes|Phospholipase|Eicosanoids |
Isotype: | IgG1 |
Shipping temp: | -20 |
Storage temp: | -20 |
Additional info: | Phospholipase A2 (PLA2) catalyzes the hydrolysis of phospholipids at the sn-2 position yielding a free fatty acid and a lysophospholipid. The release of arachidonic acid from membrane phospholipids by PLA2 is believed to be a key step in the control of eicosanoid production within the cell. Human synovial sPLA2 is a secreted, 14 kDa protein which is dependent on Ca2+ for optimal activity. Human synovial sPLA2 is 79% homologous to rat platelet and mouse type II sPLA2s. |