SRC is a non-receptor tyrosine kinase belonging to the Src subfamily. Src was the first proto-oncogene to be described and one of the first molecules demonstrated to have tyrosine kinase activity. Src is involved in a wide variety of cellular processes, including proliferation, differentiation, motility, and adhesion. Alternative splicing has been observed, including a neuron specific form with a 6aa insert in the amino-terminal half of the c-src protein.
Applications:
Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.