Home  >  Products  >  SREBF2 (Sterol Regulatory Element-binding Protein 2, SREBP-2, Class D Basic Helix-loop-helix Protein 2, bHLHd2, Sterol Regulatory Element-binding Transcription Factor 2, BHLHD2, SREBP2)
SREBF2 (Sterol Regulatory Element-binding Protein 2, SREBP-2, Class D Basic Helix-loop-helix Protein 2, bHLHd2, Sterol Regulatory Element-binding Transcription Factor 2, BHLHD2, SREBP2)

SREBF2 (Sterol Regulatory Element-binding Protein 2, SREBP-2, Class D Basic Helix-loop-helix Protein 2, bHLHd2, Sterol Regulatory Element-binding Transcription Factor 2, BHLHD2, SREBP2)

Cat no: S6505-18

Supplier: United States Biological
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Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway. Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL and HMG-CoA synthase genes. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: S6505-18
Reactivities: Human
Hosts: Rabbit
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Size: 50ug
Form: Supplied as a liquid in TBS, 0.1% BSA, 0.02% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes human SREBF2. Species sequence homology: Mouse and rat.

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