STAT 6, Phosphorylated (Tyr641) (Signal Transducer and Activator of Transcription 6, Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced, Signal Transducer And Activator Of Transcription 6 Nirs Variant 1, STAT6, D12S1644, IL-4 STAT, I

Supplier:

United States Biological

Cat no: S7972-40J

STAT 6, Phosphorylated (Tyr641) (Signal Transducer and Activator of Transcription 6, Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced, Signal Transducer And Activator Of Transcription 6 Nirs Variant 1, STAT6, D12S1644, IL-4 STAT, I

STATs (signal transducing activators of transcription) are mediators involved in cytokine signaling. In response to a specific cytokine signal, STATs move to the nucleus and induce transcription. STAT6 is activated primarily by IL-4 and IL-13. Upon activation, STAT6 is phosphorylated at Tyrosine 641 by Janus Kinases (JAK). Phosphorylated STAT6 forms head-to-tail heterodimers and translocates to the nucleus where it participates in transcriptional control. \n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1ug/ml for HRP/ECL detection\nELISA: 0.05ug/ml\nOptimal dilutions to be determined by the researcher.\n\nPositive Control (supplied): \nCell lysate of 2 x 10e6 IL-4 treated HepG2 cells. Supplied as a lyophilized powder. Reconstitute with 200ul sterile ddH2O.\n\nStorage and Stability:\nLyophilized powder may be stored at -20 degrees C. Reconstitute with sterile ddH2O, sterile 40-50% glycerol, aliquot and store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

S7972-40J

Size

100ug

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a lyophilized powder from 2X PBS, PEG, sucrose, 0.09% sodium azide. Reconstitute with 1ml sterile, ddH2O.

P Type

Mab

Purity

Purified by thiophilic adsorption and size exclusion chromatography.

Isotype

IgG1

Additional Info

Recognizes activated human STAT6 phosphorylated at Tyrosine 641 at ~97kD. The antibody does not cross react with the non-phosphorylated form of STAT6 nor with unrelated phosphorylation sites.

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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