State-of-the-Art Condenser Enhances Lyophilisation Results
The SuperCool 75 from Genevac is a state-of-the-art condenser that in conjunction with its HT-12 High Throughput Evaporator has been proven to set a new benchmark for enhanced evaporation and lyophilisation results.
Drying HPLC purification fractions, principally comprising water and acetonitrile, is a routine yet essential task in many pharmaceutical laboratories. The requirement is to dry the samples to a powder form, such that samples can be accurately weighed, easily sub-sampled and redissolved.
To provide a rapid, high-throughput alternative to freeze drying of such samples - Genevac developed its proprietary fast lyophilisation (LyoSpeed™) methodology for use on the HT-12 Evaporator. While the LyoSpeed™ has traditionally worked well for hydrophilic samples - difficulties may arise where the sample cannot dissolve in only water. In such situations, when the organic solvent is removed, the sample crashes out forming an oil which until now required further processing to achieve the desired dry powder form.