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Synaptic adhesion-like molecule 2 (SALM2, LRFN1, leucine rich repeat and fibronectin type III domain containing 1, KIAA1484, Leucine-rich repeat and fibronectin type III domain-containing protein 1)

Cat no: S9111-04A


Supplier: United States Biological
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SALM2 (synaptic adhesion-like molecule 2), is a 105kD member of the LRFN family of type I transmembrane glycoproteins. The 740aa mature human SALM2 contains a 505aa extracellular domain that includes seven leucine-rich repeats (LRR), an IgC2-like domain, and a fibronectin type-III domain. Mature human SALM2 shares 99% aa identity with mouse and rat SALM2. SALM2 co-localizes with both pre- and post-synaptic proteins at excitatory synapses in mature neurons and promotes neurite outgrowth. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 8-25ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: S9111-04A
Reactivities: Human
Hosts: Mouse
Size: 100ug
Form: Supplied as a lyophilized powder in PBS, trehalose. Reconstitute with sterile PBS to 0.5mg/ml.
P type: Mab
Isotype: IgG2B
Purity: Purified by Protein A/G affinity chromatography.
Additional info: Recognizes human SALM2. Species sequence homology: mouse and rat (99%). No cross-reactivity with recombinant human SALM1, 3, or 4.

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