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TGFb1, ID (Transforming Growth Factor, beta 1, Transforming Growth Factor-beta 1, tgfb1a, tgfb1)

TGFb1, ID (Transforming Growth Factor, beta 1, Transforming Growth Factor-beta 1, tgfb1a, tgfb1)

Cat no: T8250-16V

Supplier: United States Biological
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Transforming growth factor beta 1 (TGF-b1) is a member of the tgf family of growth factors involved in the regulation of a variety of cellular activities. In mammals, TGF-b1regulates reproduction, and ovarian function in particular. In humans, TGF-b1controls proliferation, differentiation and other functions in multiple cell types, and positively and negatively regulates a variety of growth factors. Many cells synthesize TGF-b1and have specific receptors for it. TGF-b1 is a potent stimulator of osteoblastic bone formation. The role of TGF-b1in zebrafish and other lower vertebrates is not well characterized in scientific literature, but TGF-b1 has been found to regulate oocyte maturation in fish. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Control Peptide: T8250-16P Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8250-16V
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Kohli, G et al (2003) Endocrinology. 144(5):1931-1941. 2. Munger, JS et al (1997) Kidney Int. 51:1376-1382. 3. http://www.uniprot.org/uniprot/P01137.
Additional info: Recognizes zebrafish TGF-b1a.

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