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Thromboxane B2 Express EIA Kit - Monoclonal

Thromboxane B2 Express EIA Kit - Monoclonal

Cat no: 10004023


Supplier: Cayman Chemical Company
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Thromboxane A2 (TXA2), produced from arachidonic acid, causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle. TXA2 is rapidly hydrolyzed non-enzymatically to TXB2, which is then quickly metabolized to urinary metabolites for clearance by the kidneys. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion. Cayman's Thromboxane B2 (TXB2) Express EIA is a competitive assay that provides a rapid, accurate measurement of TXB2 from plasma, urine, and cell culture supernatants. The assay typically exhibits an IC50 value (50% B/B0) of approximately 176 pg/ml and a detection limit (80% B/B0) of approximately 45 pg/ml.
Catalogue number: 10004023
Weight: 0
Form: 96 Well
P type: Assay Kits|Thromboxanes|Eicosanoids
Shipping temp: -20
Storage temp: -20
Additional info: Thromboxane A2 (TXA2) is produced from arachidonic acid by many cells and causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle. TXA2 is rapidly hydrolyzed non-enzymatically to TXB2, which is then quickly metabolized to urinary metabolites for clearance by the kidneys. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of systemic TXA2 secretion. Cayman's Thromboxane B2 (TXB2) Express EIA is a competitive assay that provides accurate measurements of TXB2 from a variety of sample types. As the name implies, this kit was designed for rapid measurements of TXB2. Features of the kit include: Fast - two hour incubation; 1 hour development . Standard curve range: 15.6 - 2,000 pg/ml . Patented AChE Tracer technology . Applicable to TXB2 measurements in plasma, urine, and cell culture.

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