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Products TIM4 Monoclonal Antibody
| Catalogue number: | 10322 |
| Hosts: | Hamster |
| Applications: | Flow Cytometry, Immunocytochemistry |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | TIM4 from hamster peritoneal cells |
| P type: | Antibodies |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | T-cell immunoglobulin and mucin domain-containing molecule (TIM4) is a type I transmembrane protein from the TIM gene family that plays a vital role in regulating immune responses, including those in allergy, asthma, transplant tolerance, autoimmunity, and viral infections. TIM4 is expressed on dendritic cells and macrophages, and these proteins bind tightly to phosphatidylserine on apoptotic cells and enhance their engulfment by macrophages. It also plays an important role in the proliferation of T helper type 2 cells. TIM4 is the natural ligand of TIM1, and this binding regulates T-cell proliferation. TIM4 expressing cells also regulate adaptive immunity. |
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