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TMPRSS3 (Transmembrane Protease, Serine 3, Tumor-associated Differentially-expressed Gene 12 Protein, Serine Protease TADG-12, UNQ323/PRO382, TADG12, ECHOS1)

TMPRSS3 (Transmembrane Protease, Serine 3, Tumor-associated Differentially-expressed Gene 12 Protein, Serine Protease TADG-12, UNQ323/PRO382, TADG12, ECHOS1)

Cat no: T8264-45C

Supplier: United States Biological
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TMPRSS3 belongs to the serine protease family. This protein contains a serine protease domain, a transmembrane domain, a LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000 Western Blot: 0.1-0.3ug/ml, observed in A431 lysates on ~48kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8264-45C
Reactivities: Human, Mouse
Hosts: Goat
Applications: ELISA, Western Blot
Size: 100ug
Form: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Lee YJ, Park D, Kim SY, Park WJ. Pathogenic mutations but not polymorphisms in congenital and childhood onset autosomal recessive deafness disrupt the proteolytic activity of TMPRSS3. J Med Genet. 2003 Aug;40(8):629-31.
Additional info: Recognizes human TMPRSS3. Species sequence homology: Mouse.

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