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TNF-b, ID (Tumor Necrosis Factor (TNF Superfamily, Member 2), Tumor Necrosis Factor alpha, Tnfb, Dr.94015, tnf, TNF alpha, DKEY-148A13.1-001)

TNF-b, ID (Tumor Necrosis Factor (TNF Superfamily, Member 2), Tumor Necrosis Factor alpha, Tnfb, Dr.94015, tnf, TNF alpha, DKEY-148A13.1-001)

Cat no: T9160-39L

Supplier: United States Biological
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Tumor necrosis factor b (TNF-b) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. The primary role of TNF is in the regulation of immune cells. TNF is also able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. TNF-b was also wildly used a a marker in zebrafish (Danio rerio) models in the studies of immune responds to the infections and other pathogenesis, degeneration, and apoptosis. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Optimal dilutions to be determined by the researcher. Control Peptide: T9160-39P Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T9160-39L
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.05% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. Vojtech, L.N., et al. (2009) Infect. Immun. 77(2):914-925. 2. Matthews, R.P., et al. (2009) Development 136(5):865-875. 3. Rodruez, I., et al. (2008) Fish Shellfish Immunol. 25(3):239-249. 4. Watzke, J., et al. (2007) Fish Shellfish Immunol. 23(4):901-905. 5. Clay, Het al. (2007) Cell Host Microbe. 2(1):29-39. 6. Nayak, A.S., et al. (2007) Toxicol. Sci. 98(1):118-124. 7. Levraud, J.P., et al. (2007) J. Immunol. 178(7):4385-4394. 8. Rojo, I., et al. (2007) Fish Shellfish Immunol. 23(6):1285-1293. 9. Eimon, P.M., et al. (2006) Cell Death Differ. 13(10):1619-1630.
Additional info: Recognizes zebrafish TNF-b.

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