

Supplier:
Cayman Chemical CompanyCat no: 160750
TRAIL Polyclonal Antibody
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SPECIFICATIONS
Catalog Number
160750
Applications
WB
Hosts
Rabbit
Form
1 ea
P Type
Antibodies|Intracellular Signaling
Weight
0
Antigen
human TRAIL amino acids 261-277 (CTNEHLIDMDHEASFFGA){6867,6889}
Storage Temp
4
Shipping Temp
4
Additional Info
Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR-1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (TNF-related apoptosis-inducing ligand) and Apo-2L (Apo-2 ligand). TRAIL is a type II membrane protein and is expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.
Applications
ELISA, IF, IP, WB
Hosts
Rabbit
Applications
ELISA, IP, WB
Hosts
Rabbit
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