Quick Search
Products TRAIL Polyclonal Antibody
| Catalogue number: | 160750 |
| Hosts: | Rabbit |
| Applications: | Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | human TRAIL amino acids 261-277 (CTNEHLIDMDHEASFFGA){6867,6889} |
| P type: | Antibodies|Intracellular Signaling |
| Shipping temp: | 4 |
| Storage temp: | 4 |
| Additional info: | Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR-1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (TNF-related apoptosis-inducing ligand) and Apo-2L (Apo-2 ligand). TRAIL is a type II membrane protein and is expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells. |
Get the Best Promotions
