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Transcription Factor IIE, alpha (TFIIEa)

Cat no: T8195-23E5

Transcription Factor IIE, alpha (TFIIEa)

The human Transcription Factor IIE (TFIIE) is composed of 56kD (a) and 34kD (b) subunits \nand is shown to be a heterotetramer. The 56-kD subunit contains a region similar to a zinc-binding domain and a region sharing homology with the catalytic loop of a kinase domain. TFIIE binds to RNA polymerase II in solution and joins the preinitiation complex probably concomitant with RNA polymerase II and TFIIF. a-TFIIEa is an affinity-purified rabbit polyclonal \nantibody raised against a recombinant full-length p56 subunit of the TFIIE complex.

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SPECIFICATIONS

Catalog Number

T8195-23E5

Size

50ug

Hosts

Rabbit

Form

Liquid. Supplied PBS.

P Type

Pab

References

1. Ohkuma et al. (1990) Proc. Natl. Acad. Sci. USA 87:9163. \n2. Inostroza et al. (1991) J. Biol. Chem. 266:9304. \n3. Peterson et al. (1991) Nature 354:369. \n4. Flores et al. (1990) J. Biol. Chem. 265:5629.

Additional Info

a-TFIIEa reacts with the p56 protein in HeLa nuclear extract by Western blotting. Recommended dilution range for Western blot analysis: 1:200 - 1:1000. \n

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