TREM-1 stimulates neutrophils and monocytes-mediated inflammatory responses. TREM-1 activation, together with LPS and other PRR ligands, amplifies the production pro-inflammatory cytokines and thus the inflammatory response. The TREM-1 pathway also plays a crucial role in septic shock. Clone has been shown to activate monocytes and granulocytes.
Applications:
Suitable for use in Flow Cytometry and Western Blot. Other applications not tested.
Recommended Dilution:
Flow Cytometry: 1:5-1:10 10ul labels 1x10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.
Recommended Secondary Antibodies:
Streptavidin APC
Streptavidin FITC
Streptavidin TRITC
Streptavidin RPE, RPE
Streptavidin HRP
Streptavidin Alk. Phos.
Storage and Stability:
May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.