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TREM-1 (Triggering Receptor Expressed on Monocytes 1, Triggering Receptor Expressed on Myeloid Cells 1 Precursor) (Biotin)

Cat no: T8282-09A

TREM-1 (Triggering Receptor Expressed on Monocytes 1, Triggering Receptor Expressed on Myeloid Cells 1 Precursor) (Biotin)

TREM-1 stimulates neutrophils and monocytes-mediated inflammatory responses. TREM-1 activation, together with LPS and other PRR ligands, amplifies the production pro-inflammatory cytokines and thus the inflammatory response. The TREM-1 pathway also plays a crucial role in septic shock. Clone has been shown to activate monocytes and granulocytes.\n\nApplications:\nSuitable for use in Flow Cytometry and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: 1:5-1:10 10ul labels 1x10e6 cells in 100ul.\nOptimal dilutions to be determined by the researcher.\n\nRecommended Secondary Antibodies:\nStreptavidin APC\nStreptavidin FITC\nStreptavidin TRITC\nStreptavidin RPE, RPE\nStreptavidin HRP\nStreptavidin Alk. Phos.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

T8282-09A

Size

25ug

Applications

FC, WB

Hosts

Mouse

Reactivities

Hum

Conjugates

Biotin

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, 1% BSA. Labeled with biotin.

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG1

Additional Info

Recognizes triggering receptor expressed on myeloid cells 1 (TREM-1), a receptor expressed on CD14+ monocytes, macrophages and neutrophils. It is also highly expressed in inflammatory lesions caused by fungi and bacteria.

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