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TREM-1 (Triggering Receptor Expressed on Monocytes 1, Triggering Receptor Expressed on Myeloid Cells 1 Precursor) (Biotin)

Cat no: T8282-09A


Supplier: United States Biological
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TREM-1 stimulates neutrophils and monocytes-mediated inflammatory responses. TREM-1 activation, together with LPS and other PRR ligands, amplifies the production pro-inflammatory cytokines and thus the inflammatory response. The TREM-1 pathway also plays a crucial role in septic shock. Clone has been shown to activate monocytes and granulocytes. Applications: Suitable for use in Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:5-1:10 10ul labels 1x10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: Streptavidin APC Streptavidin FITC Streptavidin TRITC Streptavidin RPE, RPE Streptavidin HRP Streptavidin Alk. Phos. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: T8282-09A
Reactivities: Human
Hosts: Mouse
Applications: Flow Cytometry, Western Blot
Conjugates: Biotin
Size: 25ug
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide, 1% BSA. Labeled with biotin.
P type: Mab
Isotype: IgG1
Purity: Purified by immunoaffinity chromatography.
Additional info: Recognizes triggering receptor expressed on myeloid cells 1 (TREM-1), a receptor expressed on CD14+ monocytes, macrophages and neutrophils. It is also highly expressed in inflammatory lesions caused by fungi and bacteria.

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