VAMP 1,2 (Vesicle-Associated Membrane Protein, Synaptobrevin, SYB1)

Supplier:

United States Biological

Cat no: 136854

VAMP 1,2 (Vesicle-Associated Membrane Protein, Synaptobrevin, SYB1)

VAMP-1, also known as vesicle-associated membrane protein, is an 18kD member of the synaptobrevin family of proteins. It is expressed in neurons, neutrophils, and skeletal muscle cells, and participates in vesicle fusion with the plasma membrane (1). Synaptobrevins, Syntakins and the 25kD synaptosomal associated SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane (2). VAMP-1 is also one of the key proteins in the SNARE complex which is involved in regulated exocytosis (3).\n\nApplications: \nSuitable for use in ELISA, Western Blot, and Immunohistochemistry (parrafin embedded). Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-1ug/ml\nImmunohistochemistry: parrafin\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

136854

Size

25ug

Applications

ELISA, IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.4, 50% glycerol.

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

References

1. Trimble W.S., Cowan D.M., and Scheller R.H. (1988) Proc Natl Acad Sci USA. 85: 4538-4542. 2. Nabokina S.M. (2001) Bulletin of Experimental Bio and Med. 131(2): 130-131. 3. Berglund L., Hoffman H.J., Dahl R., and Peterson T.E. (1999) Biochem Biophys Research Communicaitons. 264(3): 777-780.

Additional Info

Recognzies the human synaptic vesicle protein syanptobrevin, VAMP 1 and 2.

Alternative Names

Vesicle-Associated Membrane Protein, Synaptobrevin, SYB1

Read more on Supplier website

SUPPLIER INFO

United States Biological

Address:

4 Technology Way, Salem, MA 01970, US

Phone:

+1 800 520 3011

Website:

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